Ongoing &
Completed projects

• Stanford University & Columbia University PI: John Day, MD,PhD & Neil Schneider, MD,PhD

EXPANDED ACCESS to Jacifusen for an Individual Patient for the Treatment of ALS Associated with a FUS Mutation Clinicaltrial.gov ID: NCT04768972. MULTIPLE INDs (171038, 167330, 168210)

• Dept: Psychiatry and Behavioral Sciences - Child and Adolescent. Chair/Prof Antionio Hardan, MD

Trial of Zolpidem for Sleep in Children With Autism https://clinicaltrials.gov/ct2/show/NCT05540574

Trial of Diphenhydramine for Sleep in Children With Autismhttps://clinicaltrials.gov/ct2/show/NCT05501678

Trial of Suvorexant for Sleep in Children With Autism (https://clinicaltrials.gov/ct2/show/NCT05546554)

"A Randomized Controlled Double-Blind Trial of Sirolimus for Improving Social Abilities in People with PTEN Germline Mutations"

Intranasal Vasopressin Treatment in Children With Autism  ClinicalTrials.gov ID: NCT03204786 

A Study of N-Acetyl Cysteine in Children With Autism NCT03204786 

 

• Dept Psych/Major Laboratories and Clinical & Translational Neurosciences Incubator. Prof/Leanne Williams, MD

Mapping the Influence of Drugs of Abuse on Risk and Reward Circuits

Personalized and Translational Neuroscience Lab (PanLab) PanLab is a lab of the Stanford Center for Precision Mental Health and Wellness.

PanLab Precision Psychiatry Clinic Project --Ketamine, Buprenorphine SL

 

• Dept: Psychiatry and Behavioral Sciences – Adult. Chair/Prof Alan F. Schatzberg, MD

Regulating Circuits of the Brain Study- Ketamine (RBRAIN-KET)  08/23/2018-Active NCT03475277 

Opiate Suicide Study in Patients With Major Depression (AFSP)   10/04/2019-Active  NCT04116528 

 

• Dept: Infectious Disease. Chair/Prof Upinder Singh, Marisa Holubar, MD

Favipiravir for treatment of outpatients with asymptomatic or uncomplicated COVID-19: a double-blind randomized, placebo-controlled, phase 2 trial. medRxiv. 2021 Jan 1.

COVID-19 Outpatient Pragmatic Platform Study (COPPS): Sub-protocol: Acebilustat. NCT04662086

A Phase 2 Randomized, Double Blinded, Placebo Controlled Study of Oral Camostat Mesilate Compared to Standard of Care in Subjects with Mild COVID-19  https://classic.clinicaltrials.gov/ct2/show/NCT04524663

 

• Dept: Psych/Public Mental Health & Population Sciences. Prof Laura M. Hack, MD

The BIomarker Guided Study for Depression (BIG) 11/29/2019-Active  NCT04181736 

 

• Dept: Anesthesia - Adult Pain. Prof Jennifer Hah, MD

Low-dose Naltrexone for Bladder Pain Syndrome  ClinicalTrials.gov ID: NCT04450316 

Postoperative Pain Management in Rhinoplasty: A Randomized Controlled Trial

Pain relief after trapeziectomy without opioids: Ibuprofen and acetaminophen vs oxycodone

ClinicalTrials.gov ID: NCT04676802

 

• Dept: Med/Cardiovascular Medicine Jennifer Ann Tremmel, MD

A Randomized Controlled Study of Targeted Medical Therapy Versus Placebo for Angina and Non- Obstructive Coronary Arteries: The MVP-ANOCA study

 

• The Effects of Tranexamic Acid on Joint Inflammation and Cartilage Health in Anterior Cruciate Ligament Injured Patients

https://classic.clinicaltrials.gov/ct2/show/NCT03552705

 

• JAK Inhibition to Prevent Ventilator-induced Diaphragm Dysfunction  ClinicalTrials.gov ID: NCT03681275

• Expanded Access to L-NMMA an Individual Patient for the Treatment of of refractory locally advanced or metastatic triple negative breast cancer patients. ClinicalTrials.gov identifier (NCT number): NCT02834403

• TRIUMPH Trial Is A Prospective, Randomized, Double-Blinded, Parallel-Group, 3-Arm Trial Date: May 5, 2022 - Active Clinicaltrials.gov ID: NCT05362292 

• Effects of Sleeve Gastrectomy on Calcium Metabolism and the Skeleton Clinicaltrials.gov ID: NCT02778490

• Metformin for Pulmonary Hypertension HFpEF (PH-HFpEF) Clinicaltrials.gov ID: NCT03629340

• MOntelukast as a Potential CHondroprotective Treatment Following Anterior Cruciate Ligament Reconstruction (MOCHA • Trial) (MOCHA) Clinicaltrials.gov ID:  NCT04572256

• Letrozole in Patients With Hepatopulmonary Syndrome  Clinicaltrials.gov ID: NCT04577001

• The Effect of NAC on Lung Function and CT Mucus Score (ENACT) Clinicaltrials.gov ID: NCT03822637

• Effects of Sleeve Gastrectomy on Calcium Metabolism and the Skeleton  Clinicaltrials.gov ID: NCT02778490

• WUBI-Q Protocol, A Double-Blind Randomized Clinical Trial  Clinicaltrials.gov ID: NCT04972552

• Phase II Trial of Metformin for Pulmonary Hypertension in Heart Failure with Preserved Ejection Fraction

• Date: August 14, 2018 – Active Clinicaltrials.gov ID: NCT03629340

• A Phase 2a, randomized, double-blind, placebo-controlled study of the safety, tolerability, and efficacy of 24-hour intravenous 5-HTP (EVX-301) in Major Depressive Disorder patients with suicidal ideation

• PET IMAGING STUDY OF 89ZR-DFO-YS5 IND#128832  A First-in-Human, Pilot PET Imaging Study of 89Zr-DFO-YS5, an ImmunoPET Agent for Detecting CD46 Positive Malignancy in Men with Prostate Cancer  Clinicaltrial.gov ID: NCT05245006

• Letrozole for Treatment of Uterine Fibroids: A Randomized, Placebo-Controlled Trial

• A Double-blinded, Active Placebo-Controlled, Randomized Trial Examining the Preliminary Efficacy of Psilocybin Therapy

for People with Chronic Low Back https://classic.clinicaltrials.gov/ct2/show/NCT05351541

• MOntelukast as a potential CHondroprotective treatment following Anterior cruciate ligament reconstruction

https://clinicaltrials.gov/study/NCT04572256

• Aging Mitochondrial Fragmentation and Metabolic Flexibility Study ,Glucose and Lactate ISOTOPE INFUSION

Sponsor: Prof/Chair George Brooks, PHD

 

• Comparison of the effects of dietary folate and phytate on the absorption of zinc from either Zinc-amino acids (ZnAA) or Zinc-chloride (ZnCl2) Clinicaltrial.gov ID: NCT05273710

• Targeting Dopamine-Mediated Social Reward Sensitivity to Remediate Social Disconnection  (R61 Project)

• Advancing VR-based attentional bias as a biomarker for tobacco use disorder